Appleseed J (2002) Johnny Appleseed Speaks Entheogen Review Xi(1) 1169-1172
| #1 Posted : 10/ix/2010 ix:xx:18 PM |
Is anyone enlightened of the alkaloid content of large medicine? I'chiliad interested in getting information technology because it spreads with rhizomes unlike brachystachys however still has a reputed good alkaloid content of n,n with absolutely no gramine. I looked all over the spider web and i couldn't notice an alkaloid %
'What if everything around you, Isn't quite as information technology seems?
What if all the world you think yous know, Is an elaborate dream?
And if y'all expect at your reflection, Is it all you want information technology to exist?
What if y'all could look right through the cracks?
Would you discover yourself... Find yourself agape to run into?'
| #two Posted : 3/19/2013 9:06:10 AM |
No idea of the alkaloid content, but I have a clone too, working on exponential partitioning. It'south really hard to find any specific info about information technology, then I call up information technology's more than and then in the domain of first-time experimenters.
Johnny Appleseed reported in an Entheogen Review commodity that about a pound of dry out grass should be a dose, though I'yard guessing that could be halved for purposes of bioassaying the potency. I really wish somebody could supply the unabridged interview with J. Appleseed, information technology might have some really useful info.
See Vodsel'due south post: https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=38958&p=2
Since drying Phalaris tends to reduce the amount of alkaloids, one should be able to utilise a smaller sample of fresh grass, assuming that your extract can handle the extra water weight.
Large Medicine would seem to be a more ideal source for Phalarihuasca because information technology lacks gramine (which may be metabolized by MAO-A, which would obviously be inhibited in this situation). It has been shown in the Phalaris Assay Thread to contain hordenine, but that should be metabolized by MAO-B. Harmala alkaloids shouldn't affect MAO-B in the doses needed for MAO-A inhibition, every bit far as I can tell.
Plus, hordenine has been used every bit a supplement in the 500mg-1g range anyway.
Cautious experimentation seems warranted.
I'd likewise like to find a high 5-MeO producing strain as well, since the dose would be perhaps 1/5 of that of DMT-phalaris, and shouldn't even demand a MAOI!
| #iii Posted : iii/19/2013 12:19:57 PM |
Appleseed did notation information technology still had unpleasant stimulant effects and used a method to overcome this, as opposed to a clone
| #4 Posted : 3/19/2013 5:44:16 PM |
^then even the selected tryptamine arundinacea clones take that stimulant upshot eh..this is the simply thing holding me back from doing more bioassay work with wild arundinacea..the wild stuff is def tryptamine active and useful IME.. I will do more simply I am not keen to repeat that so soon..how did appleseed overcome the stimulant effects?..I dont remember reading about it in his work..
| #5 Posted : two/twenty/2014 11:32:34 PM |
I was just wondering if any more progress was fabricated on this?
| #6 Posted : 2/21/2014 1:20:17 AM |
Big Medicine virtually assuredly does incorporate gramine, this has been verified past GC-MS on two separate sources also every bit TLC.
Alkaloid content is in line with other varieties of P. arundinacea in the range of around .01-.05%
Fastened you will find the full interview with Johnny Appleseed:
Appleseed, J. (2002). Johnny appleseed speaks... Entheogen Review, 11(1), 1169-1172.
| #7 Posted : 2/28/2014 v:27:01 AM |
Thanks for that article, dreamer, I've been wanting to read that for a while.
Yeah, I guess I assumed Big Medicine lacked whatsoever gramine considering in the Phalaris Analysis Thread, in that location was no peak labelled for gramine in the picture. I guess I missed that slice of info somewhere.
"Thus, when a research colleague reported to me that the xv minute quick-simmer seemed to extract the tryptamine alkaloids, but get out behind the toxic elements in Phalaris, I realized that this was the breakthrough nosotros had been looking for with Phalaris."
"This new harvest technique promises to be much meliorate. Basically it involves harvesting the grass every week. The new fresh growing tips plainly produce a much college concentration of the active alkaloids. I have reports that i double scattering of the fresh growing tips extracted in acid h2o for 15 minutes provides a reliable oral feel when potentiated with Syrian Rue (Peganum harmala)."
This is applied information!
Desmanthus leptolobus looks to be the simply other North American dmt establish, just very little experimentation has been washed with information technology and information technology takes years to mature.
Phalaris is truly unique in its power to grow so apace. I know of no other tryptamine carrier that can reproduce itself and so quickly, salve the mushrooms. Tantalizing stuff for this novice researcher.
But you lot know what they say about quondam and bold mycophiles, this applies to unknown plants just too.
It looks similar nearly nobody is doing work with this plant these days, merely I'll be keeping my clone alive for the futurity.
| #8 Posted : 2/28/2014 seven:13:44 AM |
I apply arundinacea.
So practise others..they are out there.
Gramine is not an issue. It's not soluble in most of the solvents we use. Neither is hordenine.
I have taken arundinacea extracts effectually 20 times without any toxicity. Even without removing the gramine and hordenine the worst thing to happen was unpleasant stimulation.
| #9 Posted : 2/28/2014 4:48:57 PM |
You're an inspiration to me jamie, thank you for your work with arundinacea. Your reports give a flavour of this establish's spirit.
I similar the idea of a North American anahuasca considering it's so low-tech and requires piddling investment. The trouble hither is that you're extracting almost all the alkaloids from the establish, so you get the full flavor.
I'll exist looking into Autumn Olive this summer, I have a source for the plants. Last yr, I was involved in clearing them from some land to constitute fruit trees in their place, but looking at the stumps, their inner bark was a deep yellow.
I looked through the Autumn Olive thread a while ago, just nobody looks to have taken information technology orally.
This is drifting away from the topic title, I know, simply I like to ruminate about these things 
| #10 Posted : 2/28/2014 iv:59:38 PM |
Autumn Olive has been used orally by felnik..which he seems to have enjoyed.
| #11 Posted : 2/28/2014 vii:26:08 PM |
... I should probably exist studying more, thanks for the update 
| #12 Posted : 2/28/2014 viii:44:20 PM |
Source: https://www.dmt-nexus.me/forum/default.aspx?g=mobile_posts&t=16091
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